SENSITIVITAS DAN SPESIFIKASI DETEKSI Mycobacterium tuberculosis METODE TES CEPAT MOLEKULER GENEXPERT DENGAN PEMERIKSAAN MIKROSKOPIS

Abstract

The tuberculosis analysis may be made through microscopic strategies and the GeneXpert Molecular quick test. TCM is the modern-day discovery for the diagnosis via the semi-quantitative RTA technique. The rpoB gene hotspot place incorporated mycotuberculosis methods preparations automatically by extracting DNA in unmarried-use cartridges. This observation goal is to test the validity of GeneXpert TCM in comparison to microscopic methods. The form of research used is an experimental laboratory with qualitative assessment. The samples on this look had been 50 sputum samples from sufferers diagnosed with TB elderly 20-70 years with dilute situations to clarify the extent of sensitivity and specs for readings on GeneXpert and direct and 24-hour postpone the microscopic examination. The observation was conducted at the Jember Lung medical institution Laboratory. The consequences of the detection of Mycobacterium tuberculosis through the use of the TCM GeneXpert approach and direct and behind-schedule microscopic exams for twenty-four hours primarily based on Kruskal- Wallis statistical analysis acquired a significance price of zero.931 > a = 0.05, indicating no sizeable distinction between the techniques used. The distribution of suspected tuberculosis sufferers became extra male (66%) than women (34%). Most age companies infected with pulmonary TB are 40-60 years (42%). as a consequence, it may be concluded that each technique has the identical diagnostic capability in identifying Mycobacterium tuberculosis and may be used consistent with the desires, costs, and laboratory centers

Keywords: Tuberculosis, Mycobacterium tuberculosis, TCM GeneXpert, microscopic examination