INTERPRETASI HASIL KADAR SGOT DAN SGPT PENDERITA HEPATITIS B DI RUMAH SAKIT KHUSUS BEDAH HASTA HUSADA MALANG
INTERPRETATION OF SGOT AND SGPT LEVELS OF HEPATITIS B PATIENTS AT HASTA HUSADA SPECIAL SURGERY HOSPITAL MALANG
DOI:
https://doi.org/10.51804/jsh.v9i1.16910.21-26Keywords:
Hepatitis B, SGOT, SGPTAbstract
Serum Glutamic Oxaloacetic Transaminase (SGOT) and Serum Glutamic Pyruvic Transaminase (SGPT) are enzymes produced in high levels in blood serum when liver cells are severely damaged. Liver cell damage may occur due to an immune response to the Hepatitis B virus. Hepatitis B virus (HBV) is a virus that can cause an inflammation of the liver. SGOT and SGPT levels in HbsAG reactive patients can show varying levels depending on the severity of the infection and the patient's immune response. This study aimed to identify SGOT and SGPT levels in hepatitis B patients The study was conducted with a descriptive observation design. The population of hepatitis B patients were 30 people. The sampling technique was accidental sampling. The results of the SGOT study in Hepatitis B patients were 16.6% of patients had normal SGOT levels, while 83.4% of patients had elevated SGOT levels. Similarly, 5 patients (16.6%) had normal SGPT levels, and 25 patients (83.4%) had elevated SGPT levels. Among the patients, 30% were female and 70% were male. Based on age, 30% were adults, and 70% were elderly. This research can be concluded that most patients with Hepatitis B had high SGOT and SGPT levels.
References
Alwaali, M. hafiz, Nurmalasari, Y., Fitriani, D., & Zulfian. (2023). Gambaran nilai laboratorium SGOT dan SGPT pada penderita hepatitis B di RSUD Abdul Moeloek, Bandar Lampung Tahun 2021. Medula, 13(6), 1013–1019. https://www.journalofmedula.com/index.php/medula/article/download/528/660
Arikunto, S. (2015). Prosedur Penelitian Suatu Pendekatan Praktek, cet. ke-15. Ed. 15(Jakarta), Rineka Cipta.
Betharina, N., Hendriyono, FX., & Mashuri. (2017). Perbedaan Hasil Laboratorium Penderita Hepatitis B. Berkala Kedokteran, 13(1), 41–46.
Esmaeelzadeh, A., Saadatnia, H., Memar, B., Amirmajdi, E. M., & Ganji, A. (2017). Evaluation of serum HBV viral load, transaminases and histological features in chronic HBeAg-negative hepatitis B patients. 10(5), 39–43. https://pubmed.ncbi.nlm.nih.gov/28331563/
Gan, T., Cheng, N., Ding, J., Cheng, Z., Zhang, D., Li, H., Li, J., Li, N., Yang, A., Ren, X., Shi, D., Pu, H., Shen, X., Ren, X., Hu, X., Zheng, T., & Bai, Y. (2020). Effects of hepatitis B virus infection, alanine aminotransferase, aspartate aminotransferase and gamma-glutamyl transferase on prediabetes and diabetes mellitus: A cohort study. Annals of Hepatology, 19(2), 197–203. https://doi.org/10.1016/j.aohep.2019.08.008
Indah V, A. D. (2011). Hubungan Peningkatan SGPT dengan Hasil HBsAg pada Pasien Hepatitis B Di Rumah Sakit Marsudi Waluyo pada Tahun 2011. Sdh, 2(1).
Khan, S., Alam, M., Rauf, Z., Noreen, R., Shah, K., Khan, A., Ozdemir, B., & Selamoglu, Z. (2022). Comparison of Biochemical Parameters in Patients with Hepatitis B, C, and Dual Hepatitis B and C in Northwest Pakistan. Archives of Razi Institute, 77(2), 869–879. https://doi.org/10.22092/ARI.2022.357172.1988
Lestari, C. S. W., Dewi, R. M., Sunarno, S., Hasugian, A. R., Handayani, S., Maha, M. S., Panjaitan, N. S. D., Ningrum, N., Sari, M., & Fairuza, F. (2023). The effectiveness of hepatitis B vaccine in toddlers based on the five-year period national basic health research (Riskesdas 2007, 2013 and 2018) in Indonesia. PeerJ, 11, 1–23. https://doi.org/10.7717/PEERJ.15199
Nafi, V., Wardhani, P., & Setyoboedi, B. (2020). AST , ALT and Albumin Level in Chronic Hepatitis B Patients with and without Complications of Cirrhosis and Hepatocellular Carcinoma. 26(3), 344–349.
Parmono, A. T. P., Rajibsman, R., Fitriany, E., Hopmen, H., & Nuryanto, M. K. (2024). Hubungan Usia, Jenis Kelamin, SGOT, SGPT, dan HBV DNA Kuantitatif terhadap Tingkat Kekakuan Hati pada Penderita Hepatitis B Kronik. Jurnal Penelitian Inovatif, 4(2), 439–446. https://doi.org/10.54082/jupin.322
Pradnyawati, N. P. W., Lestari, A. A. W., Subawa, A. A. N., & Oka, T. G. (2018). Analisis Kadar Albumin Serum Terhadap Aspartate Transaminase ( AST ), Alanin Transaminase ( ALT ) Dan Rasio De Ritis Pada Pasien Hepatitis B Di RSUP Sanglah , Denpasar. E-Journal Medika, 7(6), 1–8.
Raheem, T., Orukpe-Moses, M., Akindele, S., Wahab, M., Ojerinola, O., Akande, D., Ochacha, I. A., & Aniedobe, M. (2021). Age, Gender Pattern and Liver Function Markers in Hepatitis B and C Seropositive Participants Attending a Health Facility in Yaba-Lagos, Nigeria. Journal of Biosciences and Medicines, 09(07), 44–58. https://doi.org/10.4236/jbm.2021.97007
Rehman, T., Hussain, M., Aslam Shad, M., Ghosh, S., & Aslam, M. (2018). Combined Effect of Age and Exposure on the Levels of Different Serum Enzymes in Workers of Pesticides Formulation Factories, Pakistan. Biochemistry & Physiology: Open Access, 07(02). https://doi.org/10.4172/2168-9652.1000238
Rosyidah, N., Widyastuti, E., Rahman, A. A., Handayani, N. S., & Belgis. (2024). CORRELATION BETWEEN SGOT AND SGPT LEVELS WITH POSITIVE HBsAg LEVELS. Journal of Vocational Health Studies, 8(1), 1–6. https://doi.org/10.20473/jvhs.v8.i1.2024.1-6
Yongpisarn, T., Namasondhi, A., Iamsumang, W., Rattanakaemakorn, P., & Suchonwanit, P. (2022). Liver fibrosis prevalence and risk factors in patients with psoriasis: A systematic review and meta-analysis. Frontiers in Medicine, 9(December), 1–13. https://doi.org/10.3389/fmed.2022.1068157
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