KESESUAIAN HASIL PEMERIKSAAN FINE NEEDLE ASPIRATION BIOPSY (FNAB) DENGAN PEMERIKSAAN HISTOPATOLOGY DALAM MENENTUKAN TUMOR PAYUDARA

ACCORDANCE OF FINE NEEDLE ASPIRATION BIOPSY (FNAB) EXAMINATION RESULTS WITH HISTOPATHOLOGY EXAMINATION IN DETERMINING BREAST TUMORS

Authors

  • Inggit Wigati Rate Universitas Maarif Hasyim Latif
  • Setyo Dwi Santoso Universitas Maarif Hasyim Latif
  • Tri Endah Anggrenani RSUD Dr. Soetomo, Surabaya, Jawa Timur, Indonesia

Keywords:

Breast tumor, FNAB, Histopatology

Abstract

Breast tumors are a collection of cells in the breast tissue that divide rapidly so that they grow and become numerous. Breast tumors are divided into 2, namely benign tumors and malignant tumors (cancer). One way to establish a diagnosis of breast tumors is by examining Fine Needle Aspiration Biopsy (FNAB) and histopathology which are the gold standard of diagnosis. The purpose of this study was to determine the suitability of FNAB examination with Histopathology in determining benign or malignant breast tumors, as well as to determine the sensitivity, specificity, positive predictive value, negative predictive value and accuracy. This study used a descriptive research method with a sample size of 96 samples in 2022. The results of the study showed that there was a match between the results of the FNAB examination and the histopathology examination in determining benign or malignant breast tumors. In this study, FNAB had a sensitivity value of 83.78%, a specificity of 95.45%, a positive predictive value of 98.41%, a negative predictive value of 63.64% and an accuracy of 86.46%. It was concluded that the Fine Needle Aspiration Biopsy (FNAB) examination was consistent with the Histopathology examination in determining tumors

References

Ahsani, R. F., & Machmud, P. B. (2019). The Association of Reproductive History with Breast Tumor in Young Women in Indonesia (Analysis of Riset PTM 2016). Media Kesehatan Masyarakat Indonesia, 15(3), 237–244. https://doi.org/10.30597/mkmi.v15i3.6278

Alam, N., Wirakusumah, F. F., & Soepardan, S. (2021). Pengetahuan dan Perilaku Sadari Berbasis Aplikasi Untuk Deteksi Dini Tumor Payudara pada Wanita Usia Subur. Jurnal Ilmiah Kesehatan, 13(1), 95–103. https://doi.org/10.37012/jik.v13i1.441

Basilion, J. P. (2001). Current and future technologies for breast cancer imaging. Breast Cancer Research, 3(1), 14–16. https://doi.org/10.1186/bcr264

Bhushan, A., Gonsalves, A., & Menon, J. U. (2021). Current state of breast cancer diagnosis, treatment, and theranostics. Pharmaceutics, 13(5), 1–24. https://doi.org/10.3390/pharmaceutics13050723

Felisha, H. F., Rinonce, H. T., Anwar, S. L., & Dwianingsih, E. K. (2019). The accuracy of fine needle aspiration biopsy to diagnose breast neoplasm. J Med Sci, 51(3), 237–245.

Juanpere, S., Perez, E., Huc, O., Motos, N., Pont, J., & Pedraza, S. (2011). Imaging of breast implants—a pictorial review. Insights into Imaging, 2(6), 653–670. https://doi.org/10.1007/s13244-011-0122-3

Nurrohmah, A., Aprianti, A., & Hartutik, S. (2022). Risk factors of breast cancer. Gaster Journal of Health Science, 20(1), 1–10. https://doi.org/10.1002/ijc.2910210406

Pelu, R. H., Beru, A. A., Surdam, Z., Dahliah, A. Z., & Nulanda, M. (2022). Perbandingan Akurasi Hasil Pemeriksaan USG Dan FNAB Terhadap Hasil Pemeriksaan Histopatologi Untuk Deteksi Tumor Payudara. Fakumi Medical Journal: Jurnal Mahasiswa Kedokteran, 2(4), 231–236.

Rachmanto, Rachmanda, A., Retnani, D. P., & Dewi, R. K. (2022). Akurasi diagnosis fine needle aspiration biopsy (fnab) tumor payudara dibandingkan dengan pemeriksaan histopatologi di instalasi patologi anatomi rs tipe b wava husada malang periode tahun 2018-2020. Universitas Brawijaya: Skripsi

Sastroasmoro, S & Ismael Sofyan. (2011). Dasar-Dasar Metodologi Penelitian Klinis, Edisi ke-4. Jakarta: Sagung Seto

Suparna, K., & Sari, L. M. K. K. . (2022). Kanker Payudara: Diagnostik, Faktor risiko, dan Stadium. Ganesha Medicine, 2(1), 42–48.

Verliyanti, V., Wiratmoko, W., & Abror, A. (2015). Perbandingan Tingkat Ketepatan Diagnosa Kanker Payudara Antara Biopsi Jarum Halus Dengan Histopatologi Di Rsud Dr. H. Abdul Moeloe K Bandar Lampung Tahun 2015. Jurnal Ilmu Kedokteran Dan Kesehatan, 2(2).

Yu, Y. H., Wei, W., & Liu, J. L. (2012). Diagnostic value of fine-needle aspiration biopsy for breast mass: A systematic review and meta-analysis. BMC Cancer, 12(1), 41. https://doi.org/10.1186/1471-2407-12-41

Zhang, X. H., & Xiao, C. (2018). Diagnostic Value of Nineteen Different Imaging Methods for Patients with Breast Cancer: A Network Meta-Analysis. Cellular Physiology and Biochemistry, 46(5), 2041–2055. https://doi.org/10.1159/000489443

Published

2024-09-30