REVIEW ARTICLE TERAPI OKSIGEN HIPERBARIK TERHADAP KINERJA MATRIX METALLOPROTEINASE-9 (MMP-9)

Authors

  • Nisa Amaliya Variansyah Universitas Hang Tuah Surabaya
  • Anisa Fathonah Universitas Hang Tuah Surabaya
  • Fakhri Muhammad Skadron 13/Serbu Pusat Penerbangan Angkatan Darat

DOI:

https://doi.org/10.51804/jsh.v5i2.1523.32-36

Abstract

Hyperbaric Oxygen Therapy (HBOT) is a therapy that uses 100% oxygen concentration. This is closely related to hyperoxygenation. Hyperbaric therapy is becoming second-line therapy for diseases related to cell recovery. In the medicine, MMP-9 is thought to increase the incidence of cancer metastasis. This is usually a contraindication to present HBO therapy and based on the results of our study, hyperbaric oxygen therapy can reduce the expression of MMP-9 when combined with primary therapy (radiotherapy). Besides that, HBOT can also increase the effectiveness of radiotherapy and HBOT can build up to MMP-9 levels.

Keywords : Hyperbaric Oxygen Therapy, Matrix Metalloproteinase-9, Metastatic Cancer

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Published

2021-12-17

Issue

Vol. 5 No. 2 (2021): September 2021

Section

Articles

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