PENGARUH AIR REBUSAN DAUN SEMANGGI AIR (Marsilea crenata) TERHADAP PENURUNAN KADAR GLUKOSA DARAH MENCIT (Mus musculus) HIPERGLIKEMIA
DOI:
https://doi.org/10.51804/jsh.v7i2.14353.63-67Abstract
Hyperglycemia is a marker of diabetes mellitus which is generally caused by damaged pancreatic ? cells which interferes with insulin secretion, causing the amount of blood glucose in the body to be uncontrolled. Marsilea crenata is known to contain several phytochemical compounds such as phenolics, flavonoids and steroids which have a positive effect on treating metabolic disorders. This study aims to determine the effect of Marsilea crenata cooking water on blood glucose levels in Mus musculus. The method used to check blood glucose levels is the POCT method. The results obtained in this study indicate that there is a difference in the average blood glucose examination in the treatment group and the control group. The average blood glucose before treatment was found to be 186.1 mg/dl, while measurements at the 4th and 7th hours after therapy with Marsilea crenata boiled water showed results of 166 mg/dl and 155.2 mg/dl. Statistical tests indicated that there was a significant difference or the effect of giving Marsilea crenata boiled water on decreasing blood glucose levels.
Keywords : Marsilea crenata, Mus musculus, Blood glucose level, Hyperglycemia
References
Adjei, D.G., Mireku-Gyimah, N.A., Sarkodie, J.A., Nguessan, B.B., Kouda, E., Amediorm J.K., Lartey, I.A., Adi-Dako, O., Asiedu-Gyekye, I.J. dan Nyarko, A.K. 2022.,Antidiabetic properties of an Ethanolic Leaf Extract of Launaea taraxacifolia (Wild.) Amin exC.Jeffrey (Asteraceae) in SD rats. Clinical Phytoscience. 8(19): 1-15
American Diabetes Association. 2010. Diagnosis and Classification of Diabetes Mellitus. Diabetes Care.33(1) : 62–69.
Behl, T., Gupta, A., Albratty, M., Najmi, A., Meraya, A.M., Alhazmi, H.A., Anwer, M.K., Bhatia, S. dan Bungau. S.G. 2022. Alkaloidal Phytoconstituents for Diabetes Management:Exploring the Unrevealed Potential. Molecules. 27(5851): 1-25
Deka, H., Choudhury, A. dan Dey, B.K. 2022. An Overview on Plant Derived Phenolic Compounds and Their Role in Treatment and Management of Diabetes. Journal of Pharmacopuncture. 25(3): 190-208
Dewiyekti, S. dan Hidayat, S. 2015. Ekstrak Daun Kelor (Moringa oleifera Lamk.)sebagai Penurun Kadar Glukosa Darah Mencit Jantan (Mus musculus L.) Hiperglikemik. Jurnal Penelitian Sains. 17(2): 72-77
Hardoko, Gunawan, W.L. dan Handayani, R. 2019. Aktivitas Inhibisi Ekstrak Daun Semanggi Air (Marsilea crenata) Terhadap Enzim HMG-KoA Reduktase.FaST –Jurnal Sains dan Teknologi. 3(1): 45-51
Hardyanto, J., Trisunuwati, P., dan Winarso, D. 2012. Efek Perasan Daun dan Tangkai Semanggi Air (Marsilea Crenata) Terhadap Penurunan Kadar Tumor Necrosis Factor Alpha (TNF-?) Dan Interleukin 1 Beta (IL-1?) Pada TikusPutih (Rattus Norvegicus) Urolithiasis. Tesis. Universitas Brawijaya, 1–11.
Indana, H.A., Puspitawati, I., Mayasari, D.S. dan Hartopo, A.B. 2023. Association of Acute Hyperglycemia and Diabetes Mellitus with Platelet-derived Microparticle (PDMP) Levels During Acute Myocardial Infarction. Asean Endocrine Journal. 38(2): 1-6
Lestari,. Zulkarnain dan Sijid, S.A.2021. Diabetes Melitus: Review Etiologi, Patofisiologi, Gejala, Penyebab, Cara Pemeriksaan, Cara Pengobatan dan Cara Pencegahan. In Prosiding Biologi Achieving the Sustainable Development Goals with Biodiversity in Confronting Climate Change. 237-241.
Ma’arif, B., Elphasa, A.A., Dewi, T.J.D., Maulina, N. dan Agil, M. 2023. Standardization of Semanggi (Marsilea crenata C. Presl.) Leaves from Benowo District, Surabaya for Standardized Herbal Raw Material. Fitofarmaka. 13(1): 20-30
Nurjanah. Azka, A. dan Abdullah, A. 2012. Aktivitas Antioksidan dan Komponen Bioaktif SemanggiAir (Marsilea crenata). Jurnal Inovasi dan Kewirausahaan. 1(3): 152-158
Parnasukma, M.D. 2018. Efek Perasan Daun dan Tangkai Semanggi Air (Marsilea crenata) sebagai Prevensi Urolithiasis pada Tikus Putih (Rattus norvegicus) Model Hiperglikemia terhadap Ekspresi Tumor Necrosis Factor Alpha (TNF?) Organ Ginjal dan Aktivitas Superoksida Dismutase (SOD). Skripsi. Universitas Brawijaya
Rulitasari, D.dan Rachmadiarti, F. 2021. Semanggi Air (Marsilea crenata) Sebagai Agen Fitoremediasi LAS Detergen. LenteraBio: Berkala Ilmiah Biologi, 9(2):99–104.
Saleh, N.J. dan Soediro, M. 2017. SERBUK SEMANGGI SEBAGAI MINUMAN HERBAL. Teknoboga, 4(1):24–29
Sarkodie JA, Squire SA, Oppong Bekoe E, Kretchy IA, Domozoro CYF, Ahiagbe KMJ, Twumasi MA, Edoh DA, Adjei De-Graft G, Sakyiama M,Lamptey VK, Obresi AS, Duncan JL, Debrah P, Frimpong-MansoS,N’guessan BB, Nyarko AK. 2015. The Antihyperglycemic, Antioxidant and Antimicrobial Activities of Ehretia cymosa. Journal of Pharmacognosy and Phytochemistry. 4(3): 105-111
Zhang, Y. danLiu,D. 2011. Flavonol kaempferol improves chronic hyperglycemia-impaired pancreatic beta-cell viability and insulinsecretory function. Eur J Pharmacol.670(1):325-332.
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